1. The chronic poisoning  of use of cannabis  sativa or indica. Chronic use reduces serum testosterone and sperm count and associated with gynecomastia.
  2. Rarely they become insane and suffer from auditory and visual disturbances, hallucinations and delusions.
  3. Heavy marijuana use may develop maniac or paranoid psychosis - the person may run amock  (ie) he develops a psychic disturbances  marked by a period of depression followed by violent attempts to kill people(impulse to mockor).
  4. He first kills a person against whom he may have real or imaginary enmity and then kills anyone that comes in his way until the homicidal tendency lasts.
  5. Then he may commit suicide or may surrender himself.
  6. Chronic use may lead to a motivational  syndrome with loss of age-appropriate  behavior, like  lethargy, lack of interest in day-to-day activities at home and at school.
  7. If the abuse is continued for a considerable time, it may lead to behavioral problems, crime and even mental derangement
  8. It does not cause physiological dependence or addiction. Cannabis compounds and LSD can be detected  in biological specimens  by radio immersion procedures.
  9. Marijuana is a potential carcinogen.


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