- Mercuric chloride, Mercuric oxide, mercuric iodide, mercuric sulfide are some of the compounds.
- Mercury has affinity for several cellular components essential for the function of survival of the cell.
- The fatal dose is 1 to 2 g of mercury chloride.
- Salivation, inflammation of gums, blue line at their junction with teeth, sore throat, GI disturbances, loosening of teeth, tremors of the tongue, involve arms & legs.
- The advanced condition is called Hatter's shake or glass blowers shakers.
- Mercurial erethism refers to psychological offers, anxiety, depression, shyness, timidity, irritability loss of confidence, delusions, hallucinations, psychosis, loss of memory & insomnia.
- Mercuria lentis is a peculiar eye change due to exposure to vapor of mercury-due to brownish deposit on the anterior lens capsule
- Acrodynia or pink disease - irritation of hand & feet followed by desquamation, loss of hair, hyperkeratosis & excessive sweating.
- Minimata disease is a type of organic mercurial poisoning due to eating of fish poisoned by mercury.
- Milk, egg white, 5% sodium formaldehyde, sulphoxycetate or 2 to 5% sodium bicarbonate may be used for gastric lavage
- Cathetics should not be given but whole bowel irrigation may be beneficial
- Penicillamine is used for less severe. Mercury vapor & inorganic mercury poisoning.
- It is given orally in a dose of 100 mg/kg every 6 hours for 5 days in acute poisoning
- BAL is the chelating agent of choice
- Demulcents
- High caloric lavage with 1:1000 solution of sulphoxylate twice daily
- Urine must be kept alkaline
- EDTA should not be used as it is nephrotic
- Haemodialysis if there is kidney damage.
- Symptomatic treatment.
Mercury is a liquid, bright, silvery
metals relative at room temperature
Chronic poisoning:
TREATMENT:
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