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CARPOPEDAL SPASM


Spasm of hand or foot seen in tetany.
Carpopedal spasm causes: Parkinson's disease, hypocalcemia, hypomagnesemia, thyroid dysfunction, Huntington's  disease, multiple sclerosis, and  Certain drugs:
  ♦   Radiocontrast
  ♦   Estrogen
  ♦  Loop diuretics
  ♦  Bisphosphonates
   Calcium supplements
   Antibiotics
   Antiepileptic drugs
   Cinacalcet.

 Acute hypocalcemia may lead to syncope, congestive heart failure (CHF), and angina due to the multiple cardiovascular effects Neuromuscular and neurologic symptoms may also occur. Neuromuscular symptoms include the following:
 Numbness and tingling sensations in the perioral area or in the fingers and toes
   Muscle cramps, particularly in the back and lower extremities; may progress to carpopedal spasm (i.e., Tetany)
   Wheezing; may develop from bronchospasm
   Dysphagia
   Voice changes (due to laryngospasm)

Neurologic symptoms of hypocalcemia include the following:
   Irritability, impaired intellectual capacity, depression, and personality changes
   Fatigue
   Seizures (E.g., grand mal, petit mal, focal)
   Other uncontrolled movements

Chronic hypocalcemia may produce the following dermatologic manifestations:
   Coarse hair
   Brittle nails
   Psoriasis
   Dry skin
   Chronic pruritus
   Poor dentition
   Cataracts

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