·        Keloid is common in blacks.
·         Common in females.
·         Genetically predisposed.
·         Often familial. Very rare in Caucasians.
·         There is a defect in maturation and stabilization of collagen fibrils.
·         Normal collagen bundles are absent.
·         Keloid continues to grow even after 6 months, maybe for many years. It extends into adjacent normal skin.
·         It is brownish-black/pinkish black(due to vascularity) in color, painful, tender and sometimes hyperaesthetic; spreads and causing itching.
·         Keloid may sometimes be associated with Ehlers-Danlos syndrome or scleroderma.
·         When keloid occurs following an unnoticed trauma without scar formation it is called a spontaneous keloid, commonly seen in negros.
·         Some keloids occasionally become nonprogressive after initial growth.
·         Pathologically, the keloid is made up of proliferating immature fibroblasts, proliferating immature blood vessels and type III thick collagen stroma.


Sites:
 Common over sternum.
 Other sites are the upper arm, chest wall, lower neck front

Differential diagnosis: Hypertrophic scar


Treatment: Controversial
·        Steroid injection: Intrakeloidal triamcinolone(stops the fibroblast proliferation and the collagen synthesis)- at regular intervals, once in 7-10 days;6-8 injections.
·        Steroid injections-excision-steroid injection.
·        Methotrexate and vitamin A therapy into the keloid
·        Silicone gel sheeting; topical retinoids.
·        Laser therapy
·        Vitamin E/Palm oil massage.
·        Intralesional excision retaining the scar margin may prevent recurrence and is ideal and better than just excision.
·        Irradiation with or without excision
·        Excision and skin grafting may be done


1 Comments

  1. A keloid scar is an enlarged, raised scar that may be pink, pink, pores and skin-coloured or darker than the encompassing skin.Keloid Treatment In Dubai They can increase after very minor skin damage, which includes an zits spot or a piercing, and unfold past the authentic vicinity of pores and skin damage.

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